Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of Probiotic Bacteria:Lactobacillus acidophilus (La-14),Bifidobacterium lactis (Bl-04),Bifidobacterium longum (Bl-05)
8 Billion CFU
*
Top Medical Research Studies
9
We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
Read More
8
Probiotics inhibit Candida biofilm growth
We investigated how probiotics, particularly Lactobacillus acidophilus and its relatives, affect the development of Candida albicans biofilms. Our findings revealed that these probiotics notably decreased biofilm growth and altered the yeast's growth behavior.
Specifically, Lactobacillus rhamnosus effectively diminished early biofilm stages. However, it didn't significantly influence mature biofilms. Overall, the lactobacilli hindered the transition of Candida from yeast to fungal forms and reduced its ability to form biofilms.
This research highlights the potential of using probiotics as a supportive treatment for yeast infections.
Specifically, Lactobacillus rhamnosus effectively diminished early biofilm stages. However, it didn't significantly influence mature biofilms. Overall, the lactobacilli hindered the transition of Candida from yeast to fungal forms and reduced its ability to form biofilms.
This research highlights the potential of using probiotics as a supportive treatment for yeast infections.
Read More
8
Lactobacilli may reduce Candida virulence
We examined how cell-free supernatants from lactobacilli, specifically L. acidophilus, L. plantarum, L. rhamnosus, and L. reuteri, affect the virulence traits of Candida parapsilosis in the context of vulvovaginal candidiasis. Our findings indicated that these lactobacilli can reduce the growth and harmful effects of C. parapsilosis, helping to enhance the vaginal lining's resistance to infection. This suggests that incorporating these lactobacilli could be beneficial in preventing yeast infections caused by non-albicans species like C. parapsilosis, although more research is needed to fully understand their effectiveness.
Read More
Most Useful Reviews
9
Stops infections
6 people found this helpful
NOW BRAND IS THE BEST. This acidophilus brand is the ONLY one that alleviates yeast infections. As someone who consumes a lot of sugar and is prone to yeast infections, I have tried every brand available. This one is truly exceptional.
Read More
9
Resolved stomach issues
4 people found this helpful
I am so thankful for this product; I had stomach issues and yeast infections before. Now, almost a year later, I have no problems. Thank you, iHerb.
Read More
10
No more infections
2 people found this helpful
Effective for helping to prevent my yeast infections. Before using this daily, I frequently got yeast infections. However, now I no longer experience them. Although I'm lactose intolerant, I have noticed a reduction in stomach pain after consuming lactose-containing products. Of course, proper hygiene is crucial, and I regularly use disposable pantyliners, which also helps prevent yeast infections. I highly recommend keeping this product in the fridge.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
- All Researches
9
We examined how a combination of ultra-low-dose estriol and lactobacilli affects vaginal health in postmenopausal women dealing with severe atrophic vaginitis while on aromatase inhibitors. Over 28 days, 16 breast cancer survivors used Gynoflor®, improving their vaginal flora. Remarkably, the lactobacillary grades increased significantly, alongside reductions in inflammatory markers like leukocytes and parabasal cells.
Although we observed a temporary spike in Candida colonization, it quickly returned to normal levels. Overall, these findings suggest that this treatment can effectively enhance vaginal health while being safe for women facing similar challenges.
Although we observed a temporary spike in Candida colonization, it quickly returned to normal levels. Overall, these findings suggest that this treatment can effectively enhance vaginal health while being safe for women facing similar challenges.
Read More
9
We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
Read More
9
We aimed to understand whether the use of probiotics could lower yeast infections in children receiving broad-spectrum antibiotics.
In a study comparing antibiotic-treated kids, we enrolled 344 who took probiotics and 376 who did not.
The results were promising, showing a significant drop in both bloodstream and urinary Candida infections among those taking probiotics.
This suggests that probiotics, including Bifidobacterium longum, can effectively help reduce yeast infections in these vulnerable patients.
In a study comparing antibiotic-treated kids, we enrolled 344 who took probiotics and 376 who did not.
The results were promising, showing a significant drop in both bloodstream and urinary Candida infections among those taking probiotics.
This suggests that probiotics, including Bifidobacterium longum, can effectively help reduce yeast infections in these vulnerable patients.
Read More
9
We evaluated the effectiveness and safety of probiotics for treating Candida-associated stomatitis in a controlled trial.
A total of 65 patients were assigned to receive either antifungal treatments alone or antifungals plus a probiotic mix containing Bifidobacterium longum.
While both groups showed a reduction in pain and hyperaemia, the probiotic group had a significantly lower Candida presence after treatment, highlighting a potential benefit in using probiotics along with conventional therapies.
However, changes in other oral bacteria were inconsistent, suggesting that more research is needed in this area.
A total of 65 patients were assigned to receive either antifungal treatments alone or antifungals plus a probiotic mix containing Bifidobacterium longum.
While both groups showed a reduction in pain and hyperaemia, the probiotic group had a significantly lower Candida presence after treatment, highlighting a potential benefit in using probiotics along with conventional therapies.
However, changes in other oral bacteria were inconsistent, suggesting that more research is needed in this area.
Read More
8
Lactobacilli may reduce Candida virulence
We examined how cell-free supernatants from lactobacilli, specifically L. acidophilus, L. plantarum, L. rhamnosus, and L. reuteri, affect the virulence traits of Candida parapsilosis in the context of vulvovaginal candidiasis. Our findings indicated that these lactobacilli can reduce the growth and harmful effects of C. parapsilosis, helping to enhance the vaginal lining's resistance to infection. This suggests that incorporating these lactobacilli could be beneficial in preventing yeast infections caused by non-albicans species like C. parapsilosis, although more research is needed to fully understand their effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Stops infections
6 people found this helpful
NOW BRAND IS THE BEST. This acidophilus brand is the ONLY one that alleviates yeast infections. As someone who consumes a lot of sugar and is prone to yeast infections, I have tried every brand available. This one is truly exceptional.
Read More
9
Resolved stomach issues
4 people found this helpful
I am so thankful for this product; I had stomach issues and yeast infections before. Now, almost a year later, I have no problems. Thank you, iHerb.
Read More
10
No more infections
2 people found this helpful
Effective for helping to prevent my yeast infections. Before using this daily, I frequently got yeast infections. However, now I no longer experience them. Although I'm lactose intolerant, I have noticed a reduction in stomach pain after consuming lactose-containing products. Of course, proper hygiene is crucial, and I regularly use disposable pantyliners, which also helps prevent yeast infections. I highly recommend keeping this product in the fridge.
Read More
9
No yeast problems
I’m using this as part of a Lyme protocol while on antibiotics. After one month, I have experienced no yeast problems, and my digestion is functioning well.
Read More
7.5
Effective fungal treatment
9 people found this helpful
Fantastic for fungal infections. This supplement effectively combats yeast infections and aids in restoring healthy gut flora. It’s much easier than consuming yoghurt filled with preservatives and sugars.
Read More
Frequently Asked Questions
9
No yeast problems
I’m using this as part of a Lyme protocol while on antibiotics. After one month, I have experienced no yeast problems, and my digestion is functioning well.
9
Resolved stomach issues
4 people found this helpful
I am so thankful for this product; I had stomach issues and yeast infections before. Now, almost a year later, I have no problems. Thank you, iHerb.
7.5
Effective fungal treatment
9 people found this helpful
Fantastic for fungal infections. This supplement effectively combats yeast infections and aids in restoring healthy gut flora. It’s much easier than consuming yoghurt filled with preservatives and sugars.
7.5
Helps blood sugar
3 people found this helpful
I take one of these twice daily. They help keep my low blood sugar in check and prevent yeast infections.
7
We examined a series of studies focusing on the effects of Lactobacillus probiotics against Candida species, which cause yeast infections affecting many adult women. Reviewing 15 articles from 2015 to 2020, we noticed that particular strains like L. acidophilus can inhibit Candida growth.
Extended use of these probiotics seems to improve treatment outcomes, especially when combined with traditional medications. Our findings suggest that the combination of the right Lactobacillus strain and duration of use plays a crucial role in tackling these stubborn infections.
Extended use of these probiotics seems to improve treatment outcomes, especially when combined with traditional medications. Our findings suggest that the combination of the right Lactobacillus strain and duration of use plays a crucial role in tackling these stubborn infections.
8
Lactobacilli may reduce Candida virulence
We examined how cell-free supernatants from lactobacilli, specifically L. acidophilus, L. plantarum, L. rhamnosus, and L. reuteri, affect the virulence traits of Candida parapsilosis in the context of vulvovaginal candidiasis. Our findings indicated that these lactobacilli can reduce the growth and harmful effects of C. parapsilosis, helping to enhance the vaginal lining's resistance to infection. This suggests that incorporating these lactobacilli could be beneficial in preventing yeast infections caused by non-albicans species like C. parapsilosis, although more research is needed to fully understand their effectiveness.
8
We examined the impacts of combining standard azole therapy with a local probiotic treatment to combat recurrent yeast infections. Involving 436 women, we divided participants into two groups: one receiving standard azole treatment alone and the other receiving the same treatment along with Lactobacillus acidophilus probiotics.
The results were telling. While over 79% of women in the azole-only group experienced lingering symptoms, those in the probiotic group saw this drop to just 31%. Additionally, microbiological success rates improved significantly, indicating that probiotics enhance the effectiveness of conventional treatments for vaginal Candida infections.
The results were telling. While over 79% of women in the azole-only group experienced lingering symptoms, those in the probiotic group saw this drop to just 31%. Additionally, microbiological success rates improved significantly, indicating that probiotics enhance the effectiveness of conventional treatments for vaginal Candida infections.
9
We aimed to understand whether the use of probiotics could lower yeast infections in children receiving broad-spectrum antibiotics.
In a study comparing antibiotic-treated kids, we enrolled 344 who took probiotics and 376 who did not.
The results were promising, showing a significant drop in both bloodstream and urinary Candida infections among those taking probiotics.
This suggests that probiotics, including Bifidobacterium longum, can effectively help reduce yeast infections in these vulnerable patients.
In a study comparing antibiotic-treated kids, we enrolled 344 who took probiotics and 376 who did not.
The results were promising, showing a significant drop in both bloodstream and urinary Candida infections among those taking probiotics.
This suggests that probiotics, including Bifidobacterium longum, can effectively help reduce yeast infections in these vulnerable patients.
8
We examined how a multispecies probiotic, including Lactobacillus acidophilus, impacts oral Candida colonization in elderly denture wearers who showed no symptoms of candidiasis. In a double-blind study, participants were divided into groups receiving either a probiotic or a placebo for five weeks.
The results indicated that those using the probiotic experienced a significant reduction in Candida levels. This suggests that probiotics could be a valuable alternative for preventing oral candidiasis, especially among vulnerable populations like the elderly.
The results indicated that those using the probiotic experienced a significant reduction in Candida levels. This suggests that probiotics could be a valuable alternative for preventing oral candidiasis, especially among vulnerable populations like the elderly.
7
Probiotics showed increased effectiveness
We examined the effectiveness of oral probiotics containing Lactobacillus acidophilus among 60 pre-menopausal women to see if they could prevent vaginal infections.
In this double-blind study, participants received different probiotic mixtures for 14 days or a placebo.
Results showed that the probiotics F_1 and F_2 increased antimicrobial activity and enhanced the detection of beneficial bacteria in the vagina.
This study lays the groundwork for future research into these probiotics’ potential for treating or preventing uro-genital infections.
In this double-blind study, participants received different probiotic mixtures for 14 days or a placebo.
Results showed that the probiotics F_1 and F_2 increased antimicrobial activity and enhanced the detection of beneficial bacteria in the vagina.
This study lays the groundwork for future research into these probiotics’ potential for treating or preventing uro-genital infections.
References
- Pimentel MMNSC, de Carvalho Alves J, Pinheiro LHS, Roselino MN. Potential Action of Probiotics Against Fungi of the Genus : A Bibliographic Review. Recent Pat Biotechnol. 2023;17:198. 10.2174/1872208317666221027093644
- Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, et al. Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System . Microbiol Spectr. 2022;10:e0269621. 10.1128/spectrum.02696-21
- Er S, İstanbullu Tosun A, Arık G, Kıvanç M. Anticandidal activities of lactic acid bacteria isolated from the vagina. Turk J Med Sci. 2019;49:375. 10.3906/sag-1709-143
- Mezzasalma V, Manfrini E, Ferri E, Boccarusso M, Di Gennaro P, et al. Orally administered multispecies probiotic formulations to prevent uro-genital infections: a randomized placebo-controlled pilot study. Arch Gynecol Obstet. 2017;295:163. 10.1007/s00404-016-4235-2
- Matsubara VH, Wang Y, Bandara HMHN, Mayer MPA, Samaranayake LP. Probiotic lactobacilli inhibit early stages of Candida albicans biofilm development by reducing their growth, cell adhesion, and filamentation. Appl Microbiol Biotechnol. 2016;100:6415. 10.1007/s00253-016-7527-3
- Donders G, Bellen G, Neven P, Grob P, Prasauskas V, et al. Effect of ultra-low-dose estriol and lactobacilli vaginal tablets (Gynoflor®) on inflammatory and infectious markers of the vaginal ecosystem in postmenopausal women with breast cancer on aromatase inhibitors. Eur J Clin Microbiol Infect Dis. 2015;34:2023. 10.1007/s10096-015-2447-1
- Vilela SF, Barbosa JO, Rossoni RD, Santos JD, Prata MC, et al. Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella. Virulence. 2015;6:29. 10.4161/21505594.2014.981486
- Kovachev SM, Vatcheva-Dobrevska RS. Local Probiotic Therapy for Vaginal Candida albicans Infections. Probiotics Antimicrob Proteins. 2015;7:38. 10.1007/s12602-014-9176-0
- Ishikawa KH, Mayer MP, Miyazima TY, Matsubara VH, Silva EG, et al. A multispecies probiotic reduces oral Candida colonization in denture wearers. J Prosthodont. 2015;24:194. 10.1111/jopr.12198
- Kumar S, Singhi S, Chakrabarti A, Bansal A, Jayashree M. Probiotic use and prevalence of candidemia and candiduria in a PICU. Pediatr Crit Care Med. 2013;14:e409. 10.1097/PCC.0b013e31829f5d88
- Li D, Li Q, Liu C, Lin M, Li X, et al. Efficacy and safety of probiotics in the treatment of Candida-associated stomatitis. Mycoses. 2014;57:141. 10.1111/myc.12116
- Kumar S, Bansal A, Chakrabarti A, Singhi S. Evaluation of efficacy of probiotics in prevention of candida colonization in a PICU-a randomized controlled trial. Crit Care Med. 2013;41:565. 10.1097/CCM.0b013e31826a409c
